Dr. Urban is a molecular geneticist. He received his postdoctoral training at the University of Hawaii and served as an Assistant Professor of Pediatrics at Washington University School of Medicine, St. Louis from 2004 to 2009.
The Urban Lab is focused on inherited diseases of the extracellular matrix, particularly the elastic fiber system. Human genetic diseases under study include supravalvular aortic stenosis, Williams syndrome and cutis laxa. Cellular and zebrafish models are used to identify key molecules and processes of elastic fiber formation and maintenance. The insights from Mendelian diseases and models are applied to understand common, complex diseases such as chronic obstructive pulmonary disease and aneurysms.
Inherited diseases of the extracellular matrix, particularly the elastic fiber, using data on humans and cellular and zebrafish models