Human Genetics, Department of Human Genetics, Genetic Counseling,Gentic Counseling Program, pittsburgh, pgh, pennsylvania, education, university, pitt, graduate school of public health, gsph
Human Genetics, Department of Human Genetics, Genetic Counseling,Gentic Counseling Program, pittsburgh, pgh, pennsylvania, education, university, pitt, graduate school of public health, gsph
Human Genetics, Department of Human Genetics, Genetic Counseling,Gentic Counseling Program, pittsburgh, pgh, pennsylvania, education, university, pitt, graduate school of public health, gsph
Faculty

Human Genetics, Department of Human Genetics, Genetic Counseling,Gentic Counseling Program, pittsburgh, pgh, pennsylvania, education, university, pitt, graduate school of public health, gsph
Daniel E. Weeks

Position: Professor
of Human Genetics and Biostatistics
Office:A303 Crabtree Hall
Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto ST, Pittsburgh, PA, 15261
Phone:412-624-5388
Email:
CV: View Weeks' CV
Education:B.A., Biology and Mathematics, Colby College, 1983
M.S., Biomathematics, University of California, 1985
Ph.D., Biomathematics (mentored by Kenneth Lange), University of California, 1988
 
Links: Dr. Weeks' web site
Faculty Research Interests Project

 
About:
Dr. Weeks' research focuses on statistical human genetics in the area of mapping susceptibility loci involved in complex diseases. He is active in external teaching activities, co-leading the annual Wellcome Trust Advanced Course on mapping complex diseases and lecturing in other courses.

Dr. Weeks' research focuses on statistical human genetics in the area of mapping susceptibility loci involved in complex diseases. His primary interest is developing new mapping methods, which involves developing algorithms and statistics, implementing them in computer programs, and testing them on real and simulated data. In addition, he is actively involved in a large number of collaborative disease gene mapping projects, all of which constantly challenge him to develop new and more useful methods for dealing with the complexities of real data. These diseases include age-related macular degeneration, obesity, otitis media, dental caries, asthma, and food allergy.
 
Research Interests:
Linkage and association analysis; statistical genetics; genetics of age-related macular degeneration, obesity, otitis media, dental caries, asthma, and food allergy
 
5 Recent Publications:

Seven New Loci Associated With Age-related Macular Degeneration
The AMD Gene Consortium (including Weeks, D. E.)
Nat Genet 2013 4; 45:433-439

ADCYAP1R1 And Asthma In Puerto Rican Children
Chen W, Boutaoui N, Brehm JM, Han YY, Schmitz C, Cressley A, Acosta-Perez E, Alvarez M, Colon-Semidey A, Baccarelli AA, Weeks DE, Kolls JK, Canino G, Celedon JC
Am J Respir Crit Care Med 2013 1; 187:584-588

Variations in apolipoprotein e frequency with age in a pooled analysis of a large group of older people.
Gareth J McKay, Giuliana Silvestri, Usha Chakravarthy, Shilpa Dasari, Lars G Fritsche, Bernhard H Weber, Claudia N Keilhauer, Michael L Klein, Peter J Francis, Caroline C Klaver, Johannes R Vingerling, Lintje Ho, Paulus T D V De Jong, Michael Dean, Julie Sawitzke, Paul N Baird, Robyn H Guymer, Dwight Stambolian, Anton Orlin, Johanna M Seddon, Inga Peter, Alan F Wright, Caroline Hayward, Andrew J Lotery, Sarah Ennis, Michael B Gorin, Daniel E Weeks, Chia-Ling Kuo, Aroon D Hingorani, Reecha Sofat, Valentina Cipriani
Am. J. Epidemiol. 2011 Jun; 173:1357-64

Enhanced genetic maps from family-based disease studies: population-specific comparisons.
Chunsheng He, Daniel E Weeks, Steven Buyske, Goncalo R Abecasis, William C Stewart, Tara C Matise
BMC Med. Genet. 2011 ; 12:15
PMC3037840    

Dissection of chromosome 16p12 linkage peak suggests a possible role for CACNG3 variants in age-related macular degeneration susceptibility.
Kylee L Spencer, Lana M Olson, Nathalie Schnetz-Boutaud, Paul Gallins, Gaofeng Wang, William K Scott, Anita Agarwal, Johanna Jakobsdottir, Yvette Conley, Daniel E Weeks, Michael B Gorin, Margaret A Pericak-Vance, Jonathan L Haines
Invest. Ophthalmol. Vis. Sci. 2011 Mar; 52:1748-54
PMC3101690    

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Human Genetics, Department of Human Genetics, Genetic Counseling,Gentic Counseling Program, pittsburgh, pgh, pennsylvania, education, university, pitt, graduate school of public health, gsph