Dr. Weeks' research focuses on statistical human genetics in the area of mapping susceptibility loci involved in complex diseases. His primary interest is developing new mapping methods, which involves developing algorithms and statistics, implementing them in computer programs, and testing them on real and simulated data. In addition, he is actively involved in a large number of collaborative disease gene mapping projects, all of which constantly challenge him to develop new and more useful methods for dealing with the complexities of real data. These diseases include age-related macular degeneration, obesity,
otitis media, dental caries, asthma, and food allergy.
Linkage and association analysis; statistical genetics; genetics of age-related macular degeneration, obesity, otitis media, dental caries, asthma, and food allergy
ADCYAP1R1 And Asthma In Puerto Rican Children Chen W, Boutaoui N, Brehm JM, Han YY, Schmitz C, Cressley A, Acosta-Perez E, Alvarez M, Colon-Semidey A, Baccarelli AA, Weeks DE, Kolls JK, Canino G, Celedon JC Am J Respir Crit Care Med 2013 1; 187:584-588
Variations in apolipoprotein e frequency with age in a pooled analysis of a large group of older people. Gareth J McKay, Giuliana Silvestri, Usha Chakravarthy, Shilpa Dasari, Lars G Fritsche, Bernhard H Weber, Claudia N Keilhauer, Michael L Klein, Peter J Francis, Caroline C Klaver, Johannes R Vingerling, Lintje Ho, Paulus T D V De Jong, Michael Dean, Julie Sawitzke, Paul N Baird, Robyn H Guymer, Dwight Stambolian, Anton Orlin, Johanna M Seddon, Inga Peter, Alan F Wright, Caroline Hayward, Andrew J Lotery, Sarah Ennis, Michael B Gorin, Daniel E Weeks, Chia-Ling Kuo, Aroon D Hingorani, Reecha Sofat, Valentina Cipriani Am. J. Epidemiol. 2011 Jun; 173:1357-64