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Laboratories
The following is a listing of the research laboratories in the Deparment of Human Genetics.
  • Dr. Barranger's lab - Molecular biology of lysosomal enzymes; gene therapy enzyme therapy; transgenic models of disease
  • Dr. Benos' lab - DNA binding by regulatory proteins; genome analysis; evolution of protein families and genomes
  • Dr. Ferrell's lab - Gene mapping; genetics of common disease including cardiovascular disease, diabetes, and cancer; human population genetics and evolution
  • Dr. Gollin's lab - Cytogenetic changes underlying various cancers; mechanisms of chromosomal instability in cancer cells; role of the cytoskeleton in chromosomal instability; mechanism of gene amplification; clinical cytogenetics
  • Dr. Hart's lab - genetics of dental and maxillofacial disorders
  • Dr. Kamboh's lab - Genetics of cardiovascular disease; genetics of Alzheimer's disease; genetics of anitphospholipid autoantibodies
  • Dr. Mehdi's lab - Antiphospholipid autoantibodies; systemic lupus erythematosus
  • Dr. Peters' lab - Genetics and transcriptomics of vascular disorders and cancers
  • Statistical Genetics - Genetics of complex diseases; genetic epidemiology; linkage analysis; statistical genetics; statistical methods for genetic linkage analysis; statistical methods for microarray and SAGE analysis

Services
This Just In...

Oct. 2002
Investigators from the Department of Human Genetics have been awarded an International Collaborative Genetics Research Training Program grant in conjunction with the Chatterjee Group from the Indian Statistical Institute Centre for Population Genomics in Calcutta, India. The award comes from the Fogarty International Center For Advanced Study in the Health Sciences (part of the U.S. National Institutes of Health) which is both co-funding the program and administering it on behalf of the partners. Read the NIH news release

Aug. 2002
Investigators from the Department of Human Genetics have used a new technique to map a region of the genome - chromosomal band 11q13 - that is amplified in a large percentage of oral cancers. They also have identified a new gene that is expressed at abnormally high levels in oral cancers when the segment is amplified. Their results are to be published the week of Aug. 5 online in the web version of Proceedings of the National Academy of Sciences. Read the UPMC press release

Projects
Project
 Lab
 Description
Tobago Prostate Cancer Study Ferrell Epidemiologic study of prostate cancer in the Tobago island population.
Baltimore Longitudinal Study of Aging Ferrell  
Lymphedema Ferrell  
Osteporosis Ferrell  
Abdominal Aortic Aneurysm Ferrell  
Obesity Ferrell  
Hypertension Ferrell  
San Luis Valley Diabetes Study Ferrell  
San Luis Valley Genetics of NIDDM Ferrell/Barmada  
Inflammatory Bowel Disease Barmada  
Familial Migraine Barmada  
International Type 2 Diabetes Consortium Barmada  
Pancreatitis Barmada  
Thyroid Hormone Phenotypes Barmada  
Genetic epidemiology of trisomies Feingold  
Statistical methods for genetic epidemiology Feingold/Weeks  
Autism Weeks  
Obesity in Samoans Weeks  
Age-related Macular Degeneration Weeks  
Endometriosis Weeks  
Type 2 Diabetes in Samoans Weeks