Susanne M. Gollin, Ph.D.

Email: sgollin@helix.hgen.pitt.edu
Phone: (412) 624-3066
Room: A308 Crabtree Hall
Position: Professor, Human Genetics

Education: B.A., Northwestern University , 1974
Ph.D., Northwestern University, 1980
Research Interests and Summary: Dr. Gollin's research specializes in cytogenetics, the study of the cellular components of heredity, or chromosomes, and how chromosome abnormalities play a role in disease. Throughout her career, Dr. Gollin has examined the cytogenetic changes underlying diseases such as head and neck cancer, childhood and adult brain tumors, leukemia, autoimmune diseases, post-transplant lymphoproliferative disease, as well as other rare tumors and inherited disorders. Much of Dr. Gollin's research is design to gain an understanding of the biology of these disorders with the goals of improving disease diagnosis and discovering genetic alterations that could serve as targets for treatment. Current research focuses on the cytogenetic changes underlying various cancers and the mechanism of chromosomal instability in cancer cells, including the role of the cytoskeleton in chromosomal instability and the process of gene amplification.

Recent Publications:

Sun PC, Uppaluri R, Schmidt AP, Pashia ME, Quant EC, Sunwoo JB, Gollin SM, Scholnick SB.

Transcript map of the 8p23 putative tumor suppressor region.
Genomics. 2001 Jul;75(1-3):17-25.

Gollin SM.

Chromosomal alterations in squamous cell carcinomas of the head and neck: window to the biology of disease.
Head Neck. 2001 Mar;23(3):238-53. Review.

Bockmuhl U, Ishwad CS, Ferrell RE, Gollin SM.

Association of 8p23 deletions with poor survival in head and neck cancer.
Otolaryngol Head Neck Surg. 2001 Apr;124(4):451-5.

Rao UN, Gollin SM, Beaves S, Cieply K, Nalesnik M, Michalopoulos GK.

Comparative genomic hybridization of hepatocellular carcinoma: correlation with fluorescence in situ hybridization in paraffin-embedded tissue.
Mol Diagn. 2001 Mar;6(1):27-37.

Woolley PV, Gollin SM, Riskalla W, Finkelstein S, Stefanik DF, Riskalla L, Swaney WP, Weisenthal L, McKenna RJ Jr.

Cytogenetics, immunostaining for fibroblast growth factors, p53 sequencing, and clinical features of two cases of cystosarcoma phyllodes.
Mol Diagn. 2000 Sep;5(3):179-90.

Shuster MI, Han L, Le Beau MM, Davis E, Sawicki M, Lese CM, Park NH, Colicelli J, Gollin SM.

A consistent pattern of RIN1 rearrangements in oral squamous cell carcinoma cell lines supports a breakage-fusion-bridge cycle model for 11q13 amplification.
Genes Chromosomes Cancer. 2000 Jun;28(2):153-63.

Other Publications: Click here to perform an automatic search for a listing of all Susanne Gollin's publications and their abstracts through the National Library of Science's PubMed service.

Click here to view Dr. Gollins's Faculty Interests Page on the GSPH web site

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Email:	sgollin@helix.hgen.pitt.edu
Phone:	(412) 624-3066
Room:	A308 Crabtree Hall
Position:	Professor, Human Genetics
Education:	B.A., Northwestern University , 1974 Ph.D., Northwestern University, 1980
Research Interests and Summary:	Dr. Gollin's research specializes in cytogenetics, the study of the cellular components of heredity, or chromosomes, and how chromosome abnormalities play a role in disease. Throughout her career, Dr. Gollin has examined the cytogenetic changes underlying diseases such as head and neck cancer, childhood and adult brain tumors, leukemia, autoimmune diseases, post-transplant lymphoproliferative disease, as well as other rare tumors and inherited disorders. Much of Dr. Gollin's research is design to gain an understanding of the biology of these disorders with the goals of improving disease diagnosis and discovering genetic alterations that could serve as targets for treatment. Current research focuses on the cytogenetic changes underlying various cancers and the mechanism of chromosomal instability in cancer cells, including the role of the cytoskeleton in chromosomal instability and the process of gene amplification.